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Blood irradiation therapy is an alternative medical procedure in which the blood is exposed to low-level light (often laser light) for therapeutic reasons. [1] The practice was originally developed in the United States, [1] but most recent research on it has been conducted in Germany (by UV lamps) and in Russia (in all variants).
A person employed in this field is referred to as an immunohematologist or colloquially as a blood banker. Their day-to-day duties include blood typing, cross-matching and antibody identification. [1] [citation needed] Immunohematology and Transfusion Medicine is a medical post graduate specialty in many countries.
The patient that develops neutropenia after radiation is susceptible to irradiation damage to other tissues, such as the gastrointestinal tract, lungs and the central nervous system. These patients may require therapeutic interventions not needed in other types of neutropenic infections.
However, the term should only be used when truly local treatments result in systemic effects. For instance, chemotherapeutics commonly circulate through the blood stream and therefore exclude the possibility of any abscopal response. The mediators of the abscopal effect of radiotherapy were unknown for decades.
Irradiation is used in diagnostic imaging, cancer therapy and blood transfusion. [5] In 2011 researchers found that irradiation was successful in the novel theranostic technique involving co-treatment with heptamethine dyes to elucidate tumor cells and attenuate their growth with minimal side effects. [6] [7]
Therefore, such patients may be issued irradiated blood components, including irradiated red blood cells. [39] [40] X-ray or gamma sources are usually used for irradiation. [40] When blood components are irradiated, the DNA is destroyed in any remaining white blood cells (leucocytes), which stops the leucocytes from being able to proliferate ...
Prevention includes gamma irradiation of the lymphocyte-containing blood components such as red blood cells, platelets and granulocytes. Irradiated blood components should be issued in the following situations: [7] Intrauterine transfusions; Prematurity, low birthweight, or erythroblastosis fetalis in newborns; Congenital immunodeficiencies
Total body irradiation (TBI) is a form of radiotherapy used primarily as part of the preparative regimen for haematopoietic stem cell (or bone marrow) transplantation. As the name implies, TBI involves irradiation of the entire body, though in modern practice the lungs are often partially shielded to lower the risk of radiation-induced lung ...