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  2. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    However, the increased rate of calcium sequestration also leads to an increase in lusitropy. Sensitizing troponin-C to the effects of calcium. Phosphorylating L-type calcium channels. This will increase their permeability to calcium, allowing more calcium into the myocyte cells, increasing contractility.

  3. Bowditch effect - Wikipedia

    en.wikipedia.org/wiki/Bowditch_effect

    When a higher heart rate occurs, for example due to adrenergic stimulation, the L-type calcium channel has increased activity. The sodium-calcium exchanger (which allows 3 Na + to flow down its electrochemical gradient in exchange for 1 Ca ++ ion to flow out of the cell) works to decrease the levels of intracellular calcium.

  4. Calcification - Wikipedia

    en.wikipedia.org/wiki/Calcification

    Calcification of soft tissue (arteries, cartilage, heart valves, [1] [2] etc.) can be caused by vitamin K 2 deficiency or by poor calcium absorption due to a high calcium/vitamin D ratio. This can occur with or without a mineral imbalance. A common misconception is that calcification is caused by excess amount of calcium in diet. Dietary ...

  5. Lusitropy - Wikipedia

    en.wikipedia.org/wiki/Lusitropy

    Lusitropy or lucitropy is the rate of myocardial relaxation. The increase in cytosolic calcium of cardiomyocytes via increased uptake leads to increased myocardial contractility (positive inotropic effect), but the myocardial relaxation, or lusitropy, decreases.

  6. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    [17] [18] The influx of calcium ions (Ca 2+) through L-type calcium channels also constitutes a minor part of the depolarisation effect. [19] The slope of phase 0 on the action potential waveform (see figure 2) represents the maximum rate of voltage change of the cardiac action potential and is known as dV/dt max.

  7. Here Are Cardiologist-Approved Ways to Lower Your Resting ...

    www.aol.com/cardiologist-approved-ways-lower...

    Science & Tech. Sports. Weather. 24/7 ... some medications for thyroid conditions and migraines can also affect your resting heart rate,” she notes. ... If your heart rate is excessively high or ...

  8. Calcium in biology - Wikipedia

    en.wikipedia.org/wiki/Calcium_in_biology

    The US Institute of Medicine (IOM) established Recommended Dietary Allowances (RDAs) for calcium in 1997 and updated those values in 2011. [6] See table. The European Food Safety Authority (EFSA) uses the term Population Reference Intake (PRIs) instead of RDAs and sets slightly different numbers: ages 4–10 800 mg, ages 11–17 1150 mg, ages 18–24 1000 mg, and >25 years 950 mg. [10]

  9. Calcium-induced calcium release - Wikipedia

    en.wikipedia.org/wiki/Calcium-induced_calcium...

    When an action potential depolarizes the cell membrane, voltage-gated Ca 2+ channels (e.g., L-type calcium channels) are activated. CICR occurs when the resulting Ca 2+ influx activates ryanodine receptors on the SR membrane, which causes more Ca 2+ to be released into the cytosol.