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diazepam – benzodiazepine used to treat status epilepticus, also used as a preanaesthetic and a sedative; dichlorophene – fungicide, germicide, and antimicrobial agent, also used for the removal of parasites; diphenhydramine – histamine blocker; doxycycline – antibiotic, also used to treat Lyme disease
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [15] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [15]
Individual dogs of any breed can have a profound reaction characterized by hypotension, especially if there is an underlying heart problem. In giant-breed dogs and sighthounds , the sedative effects of acepromazine may last for 12–24 hours, which is much longer than the usual 3–4 hours.
Finally, note that the benzodiazepine core is a privileged scaffold, which has been used to derive drugs with diverse activity that is not limited to the GABA A modulatory action of the classical benzodiazepines, [60] such as devazepide and tifluadom, however these have not been included in the list below. 2,3-benzodiazepines such as tofisopam ...
Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1] Tables of this general type are also available for NSAIDs , benzodiazepines , depressants , stimulants , anticholinergics and others.
Zolazepam [2] (Flupyrazapon) is a pyrazolodiazepinone derivative structurally related to the benzodiazepine drugs, which is used as an anaesthetic for a wide range of animals in veterinary medicine. Zolazepam is usually administered in combination with other drugs such as the NMDA antagonist tiletamine or the α2 adrenergic receptor agonist ...
Imepitoin acts as a low-affinity (4,350–5,140 nM; relative to K i = 6.8 nM for diazepam and K i = 1.7 nM for clonazepam) partial agonist of the benzodiazepine site of the GABA A receptor (up to 12–21% of the maximal potentiation of diazepam, a full agonist of this site). [1] It is the first partial agonist to be approved for the treatment ...
A benzodiazepine can be placed into one of three groups by its elimination half-life, or time it takes for the body to eliminate half of the dose. [196] Some benzodiazepines have long-acting active metabolites , such as diazepam and chlordiazepoxide, which are metabolised into desmethyldiazepam .