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It is used as a cream or ointment applied to the skin. [6] Common side effects include itchiness and rash at the site of application, headache, and nausea. [6] Long term use may result in increased growth of fungi. [6] Use during pregnancy and breastfeeding appears to be safe. [6] Mupirocin is chemically a carboxylic acid. [8]
However, widespread use of mupirocin is associated with development of mupirocin-resistant strains of MRSA, with one hospital in Canada experiencing an increase from 2.7% to 65% resistant strains in three years. [78]
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [1] [2] It contains the three antibiotics neomycin, polymyxin B, and bacitracin. [1] It is for topical use. [3] [4]
Foban (topical cream in New Zealand) Betafusin (fusidic acid/betamethasone valerate topical cream in Greece) Betafucin (2% fusidic acid/1% betamethasone valerate topical cream in Egypt)(of Delta Pharma S.A.E., A.R.E. (Egypt)) Fusimax (of Roussette in India) Fusiderm (topical cream and ointment by Indi Pharma in India) Fusid (in Nepal)
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