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Mutations in CDK13 were first identified as pathogenic in 2016, when they were identified in 7 individuals from a large cohort of 1,891 patients with congenital heart defects in a study by Sifrim et al. [2] [3] [8] Mutations in CDK13 were then found again in 2017 in 11 individuals from an even larger cohort of 4,293 patients from the UK and ...
On July 26, 1764, four Delaware (Lenape) Native Americans entered a settlers' log schoolhouse in the Province of Pennsylvania and killed the schoolmaster, Enoch Brown, and ten students. One other student named Archie McCullough was wounded. [1] Historian Richard Middleton described the massacre [2] as "one of the most notorious incidents" of ...
The incident was formerly the deadliest American mass shooting and is currently the third-deadliest. December 14, 2012: Newtown, Connecticut: 28 [n 1] 2: Sandy Hook Elementary School shooting: 20-year-old Adam Lanza killed twenty-six people and himself. He first killed his mother at their shared home before taking four of her guns and driving ...
The Gun Violence Archive, which defines a mass shooting as four or more people shot in one incident (not including the shooter), reports more than 14,000 people killed and over 29,000 injured in 2017.
2017 Aztec High School shooting: William Atchison, 21-year-old former male student sneaked into Aztec High School disguised as a student and hid in an unlocked washroom with a Glock 9mm handgun hidden in his bag. He retreated from the washroom after being spotted by a school custodian who chased him shouting "active shooter" and "lockdown".
Lists of school shootings in the United States include: List of school shootings in the United States (before 2000) List of school shootings in the United States (2000–present) List of school shootings in the United States by death toll
These uncommon congenital disorders are characterized by defects in the heart, spleen and paired organs such as the lungs and kidneys. Another name is "asplenia-cardiovascular defect-heterotaxy". [2] Right atrial isomerism is named for its discoverer, Swedish pathologist Biörn Ivemark. [3]
A double inlet left ventricle (DILV) or "single ventricle", is a congenital heart defect appearing in 5 in 100,000 newborns, where both the left atrium and the right atrium feed into the left ventricle. The right ventricle is hypoplastic or does not exist. Both atria communicate with the ventricle by a single atrio-ventricular valve.