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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Patients who are drug withdrawal states or are non-compliant with psychotropic drugs [6] [11] Undiagnosed/ untreated psychiatric patients [23] [6] People with severe manic episodes [12] [6] Sleep deprivation which can trigger and even worsen acute manic episodes [6] People with medical history of neurological and physiological conditions [12]
Mania is a syndrome with multiple causes. [6] Although the vast majority of cases occur in the context of bipolar disorder, it is a key component of other psychiatric disorders (such as schizoaffective disorder, bipolar type) and may also occur secondary to various general medical conditions, such as multiple sclerosis; certain medications may perpetuate a manic state, for example prednisone ...
Onset of Bipolar Disorder. Signs of bipolar disorder generally emerge in young adulthood. Research suggests that 70 percent of people with bipolar disorder experience their first manic episode ...
[29] [30] [31] To fit the definition of a manic episode, these behaviors must impair the individual's ability to socialize or work. [29] [31] If untreated, a manic episode usually lasts three to six months. [32] In severe manic episodes, a person can experience psychotic symptoms, where thought content is affected along with mood. [31]
From this pool, scientists identified about 1,300 people presenting with a first-episode psychosis or mania, and another about 2,700 people — considered the control group — with a psychiatric ...
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