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Helicases are a class of enzymes that are vital to all organisms. Their main function is to unpack an organism's genetic material. Helicases are motor proteins that move directionally along a nucleic double helix, separating the two hybridized nucleic acid strands (hence helic-+ -ase), via the energy gained from ATP hydrolysis. There are many ...
Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family. [ 5 ] Helicase enzymes generally unwind and separate double-stranded DNA .
DEAD box proteins are helicases that perform unwinding in an energy-dependent approach and are able to perform these snRNP rearrangements in a quick and efficient manner. [13] There are three DEAD box proteins in the yeast system, Sub2, Prp28, and Prp5, which have been proven to be required for in vivo splicing. [ 13 ]
Helicase, POLQ-like, also known as Helicase Q (HELQ), HEL308 and Holliday junction migration protein, encoded by the gene HELQ1, is a DNA helicase found in humans, archea and many other organisms. [5] HelQ is a replication-linked repair helicase that preserves DNA integrity through helping in the repair of DNA that has become damaged. [6]
Bloom syndrome protein is a protein that in humans is encoded by the BLM gene and is not expressed in Bloom syndrome. [5]The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities.
A helicase–primase complex (also helicase-primase, Hel/Prim, H-P or H/P) is a complex of enzymes including DNA helicase and DNA primase. A helicase-primase associated factor protein may also be present. [1] The complex is used by herpesviruses, in which it is responsible for lytic DNA virus replication.
RecQ helicase is a family of helicase enzymes initially found in Escherichia coli [1] that has been shown to be important in genome maintenance. [ 2 ] [ 3 ] [ 4 ] They function through catalyzing the reaction ATP + H 2 O → ADP + P and thus driving the unwinding of paired DNA and translocating in the 3' to 5' direction.
13211 Ensembl ENSG00000135829 ENSMUSG00000042699 UniProt Q08211 O70133 RefSeq (mRNA) NM_001357 NM_030588 NM_007842 RefSeq (protein) NP_001348 NP_031868 NP_001392438 Location (UCSC) Chr 1: 182.84 – 182.89 Mb Chr 1: 153.33 – 153.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ATP-dependent RNA helicase A (RHA ; also known as DHX9, LKP, and NDHI) is an enzyme that in humans is ...