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Niemann isolated cocaine from coca leaves in 1859. In the 19th century, there was great interest among European chemists in the effects of coca leaves discovered in Latin America . In 1855 the chemist Friedrich Gaedcke had published a treatise on an active alkaloid extract of the coca leaf he called erythroxyline , after the genus Erythroxylum ...
On a New Organic Base in the Coca Leaves is an 1860 dissertation written by Albert Niemann. [1] Its title in German is Über eine neue organische Base in den Cocablättern. The piece describes, in detail, how Niemann isolated cocaine, a crystalline alkaloid. It also earned Niemann his Ph.D., and is now in the British Library. He wrote of the ...
Coca-Cola used coca leaf extract in its products from 1885 until about 1903, when it began using decocainized leaf extract. [ 9 ] [ 10 ] [ 11 ] Extraction of cocaine from coca requires several solvents and a chemical process known as an acid–base extraction , which can fairly easily extract the alkaloids from the plant.
1855: First synthesis of the cocaine alkaloid by Friedrich Gaedcke; [336] development of an improved purification process by Albert Niemann in 1859–1860, who also coined the name "cocaine". [337] First commercial production of cocaine began in 1862 in Darmstadt by Merck.
From that expedition he brought back enough coca leaves that Albert Niemann subsequently isolated cocaine. [1] After returning in 1859, Scherzer was appointed as a councillor of the board of trade, held an office in the bureau of foreign relations, and was tasked with compiling the commercial statistics of the empire.
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Working with coca leaves, Gaedcke isolated the cocaine molecule. [3] Gaedcke named the alkaloid “erythroxyline,” and published a description in the journal Archiv der Pharmazie in 1855. [ 4 ] [ 5 ] He described the alkaloid as being of small crystal molecules with needle-like points on four to six sides. [ 3 ]