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GLP-1 receptor agonists are already being used to treat alcohol use disorder in some circumstances, Dr. Sarhan says, noting that this is a growing trend in addiction disorder medicine.
The researchers concluded that GLP-1 receptor agonist medications—especially semaglutide—"offer promise as a novel treatment to reduce alcohol consumption and to prevent development of alcohol ...
A new study has found that semaglutide — the active substance in Ozempic and Wegovy — may help reduce alcohol cravings in people with AUD. Despite the availability of treatment options, past ...
Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. [8] It has also been found effective in the treatment of other addictions and may be used for them off-label. [12]
GLP-1 agonists are under development for substance use disorder, a condition with few pharmacological treatment options. They reduce the self-administered intake of drugs and alcohol in non-human animals, though this effect has not been proven in humans. The mechanism of this addiction-reducing effect is unknown. [24]
When used alone, acamprosate is not an effective therapy for alcohol use disorder in most individuals, [7] as it only addresses withdrawal symptoms and not psychological dependence. Acamprosate is a medication that works in the brain to treat alcohol use disorder. Acamprosate works by decreasing cravings and urges to use alcohol.