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List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
comphrey, blackwort, common comfrey, slippery root [4] Symphytum officinale: Liver damage, [4] [5] cancer [4] Country mallow: heartleaf, silky white mallow Sida cordifolia "Heart attack, heart arrhythmia, stroke, death" [4] Dan Shen red sage, Chinese sage, tan shen Salvia miltiorrhiza
Marjoram (/ ˈ m ɑːr dʒ ər ə m /, [2] Origanum majorana) is a cold-sensitive perennial herb or undershrub with sweet pine and citrus flavours. In some Middle Eastern countries, marjoram is synonymous with oregano, and there the names sweet marjoram and knotted marjoram are used to distinguish it from other plants of the genus Origanum.
With continued use, steroids have dangerous side effects which include, but are not limited to: high blood pressure, diabetes, weight gain, osteoporosis, stomach ulcers, adrenal insufficiency ...
There are two variants of the estrogen receptor, alpha and beta and many phytoestrogens display somewhat higher affinity for ER-β compared to ER-α. [14] The key structural elements that enable phytoestrogens to bind with high affinity to estrogen receptors and display estradiol-like effects are: [2]
In particular, estrogen applied topically may have a different spectrum of side effects than when administered orally, [11] and transdermal estrogens do not affect clotting as they are absorbed directly into the systemic circulation, avoiding first-pass metabolism in the liver.
Estrogen also plays very important role in animal metabolism balance. These unexpected diseases hindered estrogen to get involved in neurodegenerative disease therapy. So, when applying estrogen-like drugs to relieve neurodegenerative diseases, the concentration should be restrictly controlled to avoid these side effects. [citation needed]
Side effects of EEs include nausea, breast tension, edema, and breakthrough bleeding among others. [8] It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. [5] [3] [4] EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. [5] EEs were introduced for medical use by 1970 ...