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Unlike HUS and aHUS, [39] [40] TTP is known to be caused by a defect in the ADAMTS13 protein, [41] so a lab test showing ≤5% of normal ADAMTS13 levels is indicative of TTP. [28] ADAMTS13 levels above 5%, coupled with a positive test for shiga-toxin / enterohemorrhagic E. coli (EHEC), are more likely indicative of HUS, [ 42 ] whereas absence ...
Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. [1] [2] Thrombosis may occur in veins (venous thrombosis) or in arteries (arterial thrombosis).
Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes.
Platelet concentrations vary between individuals and over time, with the population average between 250,000 and 260,000 cells per mm 3 (equivalent to per microliter), but the typical laboratory accepted normal range is between 150,000 and 400,000 cells per mm 3 or 150–400 × 10 9 per liter.
Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding. Giant platelets cannot stick adequately to injured blood vessel walls, resulting in abnormal bleeding when injured.
The normal range for a healthy person not using warfarin is 0.8–1.2, and for people on warfarin therapy an INR of 2.0–3.0 is usually targeted, although the target INR may be higher in particular situations, such as for those with a mechanical heart valve. If the INR is outside the target range, a high INR indicates a higher risk of bleeding ...
Testosterone levels in males and females ; Total testosterone Stage Age range Male Female Values SI units Values SI units ; Infant: Premature (26–28 weeks) 59–125 ng/dL: 2.047–4.337 nmol/L
Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. ...