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The opponents and supporters of chloroform disagreed on the question of whether the medical complications were due to respiratory disturbance or whether chloroform had a specific effect on the heart. Between 1864 and 1910, numerous commissions in Britain studied chloroform but failed to come to any clear conclusions.
The use of chloroform anesthesia expanded rapidly thereafter in Europe. Chloroform began to replace ether as an anesthetic in the United States at the beginning of the 20th century. It was soon abandoned in favor of ether when its hepatic and cardiac toxicity, especially its tendency to cause potentially fatal cardiac dysrhythmias, became ...
Sir James Young Simpson, 1st Baronet FRSE FRCPE FSA Scot (7 June 1811 – 6 May 1870) was a Scottish obstetrician and a significant figure in the history of medicine.He was the first physician to demonstrate the anaesthetic properties of chloroform in humans and helped to popularize its use in medicine.
Early chloroform bottle, Hunterian Museum, Glasgow. Dr Robert Mortimer Glover FRSE (1815-1859) was an English physician. In 1838 he co-founded the Paris Medical Society and served as its first Vice President.
Chloroform; Ether; Several medical anesthetics are used as recreational drugs, including diethyl ether (a drug that is no longer used medically, due to its high flammability and the development of safer alternatives) and nitrous oxide, which has been widely used since the late 20th century by dentists as an anti-anxiety drug and mild anesthetic ...
The Russian Health Minister Yuri Shevchenko later stated that the incapacitating agent used was a fentanyl derivative. Scientists at Britain's chemical and biological defense labs at Porton Down analyzed residue from the clothing of three hostages and the urine of one hostage rescued during the Moscow theater hostage crisis and found two ...
In 1847, Scottish obstetrician James Young Simpson was the first to demonstrate the anesthetic properties of chloroform on humans and helped to popularize the drug for use in medicine. [57] This first supply came from local pharmacists, James Duncan and William Flockhart , and its use spread quickly, with 750,000 doses weekly in Britain by 1895.
ACE mixture is an historical anaesthetic agent for general anaesthesia.It was first suggested by George Harley [1] and first used in England around 1860. In 1864 it was recommended for use by the Royal Medical and Surgical Society's Chloroform Committee.