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The development of the nervous system in humans, or neural development, or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience.These describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development, and continues to develop postnatally.
Corticogenesis: younger neurons migrate past older ones using radial glia as a scaffolding. Cajal–Retzius cells (red) release reelin (orange). Neuronal migration is the method by which neurons travel from their origin or birthplace to their final position in the brain. There are several ways they can do this, e.g. by radial migration or ...
The neurons in each cortex are selectively pruned, leaving connections that are made with the functionally appropriate processing centers. Therefore, the neurons in the visual cortex prune the synapses with neurons in the spinal cord, and the motor cortex severs connections with the superior colliculus. This variation of pruning is known as ...
Dendritic spines exhibit three main morphologies: filopodia, thin spines, and mushroom spines. The filopodia play a role in synaptogenesis through initiation of contact with axons of other neurons. Filopodia of new neurons tend to associate with multiply synapsed axons, while the filopodia of mature neurons tend to sites devoid of other partners.
Studies in children with early childhood brain injuries have shown that neural adaptations slowly occur after the injury. [28] Children with early injuries to the linguistics, spatial cognition and affective development areas of the brain showed deficits in those areas as compared to those without injury. Due to neural adaptations, however, by ...
These are collectively referred to as postsynaptic receptors, since they are located on the membrane of the postsynaptic cell. Postsynaptic potentials are important mechanisms by which neurons communicate with each other allowing for information processing, learning, memory formation, and complex behavior within the nervous system. [2]
Synaptic scaling is a primary mechanism by which a neuron is able to stabilize firing rates up or down. [ 16 ] Synaptic scaling serves to maintain the strengths of synapses relative to each other, lowering amplitudes of small excitatory postsynaptic potentials in response to continual excitation and raising them after prolonged blockage or ...
Neural facilitation, also known as paired-pulse facilitation (PPF), is a phenomenon in neuroscience in which postsynaptic potentials (PSPs) (EPPs, EPSPs or IPSPs) evoked by an impulse are increased when that impulse closely follows a prior impulse.