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The Guideline Development Group then finalises the recommendations and the National Collaboration Centre produces the final guideline. This is submitted to NICE to formally approve the guideline and issue the guidance to the NHS. [citation needed] To date NICE has produced more than 200 different guidelines. [27]
Although the use of the term DMARDs was first propagated in rheumatoid arthritis (hence their name), the term has come to pertain to many other diseases, such as Crohn's disease, lupus erythematosus, Sjögren syndrome, immune thrombocytopenic purpura, myasthenia gravis, sarcoidosis, and various others. [citation needed]
Their purpose is to engage clinicians in systematic evaluation of their clinical practice against standards (often set by NICE), and to encourage improvement in the quality of care. This programme is gradually being extended to other areas of healthcare, working with clinical, patient and professional advisory groups.
European Union: In the EU, Good Clinical Practice is backed and regulated by formal legislation contained in the Clinical Trial Regulation (Officially Regulation (EU) No 536/2014 of the European Parliament and of the Council of 16 April 2014 on clinical trials on medicinal products for human use, and repealing Directive 2001/20/EC). [3]
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]
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Arthritis is predominantly a disease of the elderly, but children can also be affected by the disease. [105] Arthritis is more common in women than men at all ages and affects all races, ethnic groups and cultures. In the United States, a CDC survey based on data from 2013 to 2015 showed 54.4 million (22.7%) adults had self-reported doctor ...
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