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Lamotrigine is expressed in breast milk; the manufacturer recommends carefully weighing the benefits and risks of taking lamotrigine while breastfeeding. [61] However, some studies suggest that lamotrigine is safe to use while breastfeeding. [62] A frequently updated review of scientific literature rates lamotrigine as L3: moderately safe. [63]
Its use later on during pregnancy also increases the risk of preterm labour (odds ratio: 1.51) and low birth weight (odds ratio: 1.67). [17] [18] Animal studies have yielded similarly discouraging results. [3] It appears to be safe for use during breastfeeding as long as the baby is healthy. [19]
Benzonatate was first made available in the United States in 1958 as a prescription medication for the treatment of cough in individuals over the age of 10. [24] [25] There is a variety of prescription opioid-based cough relievers, such as hydrocodone and codeine, but have unwanted side effects and potential of abuse and diversion. [22]
It is considered safe during pregnancy, but it can pass into breast milk and may harm a nursing baby. [11] Ipratropium bromide was patented in 1966, and approved for medical use in 1974. [12] It is on the World Health Organization's List of Essential Medicines, the most important medicines needed in a health system. [13]
While it has not been properly studied in pregnancy, it appears to be safe. [7] It has been alleged to work in 2023 [4] by making airway secretions more liquid, even as it has been demonstrated not to work. [5] [6] Guaifenesin has been used medically since at least 1933. [8] It is available as a generic medication and over-the-counter (OTC).
Promethazine is preferred during pregnancy because it is an older drug and there is more data regarding the use of it during pregnancy. Second-choice medications, which are used if Promethazine isn't tolerated or the patient cannot take it, are metoclopramide or prochlorperazine. [15] [13]
Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup. It was patented in 1966 and came into medical use in 1979. [1]
Breastfeeding and medications is the description of the medications that can be used by a breastfeeding mother, and the balance between maternal health and the safety of the breastfeeding infant. [1] [2] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities. [3]