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Pseudoxanthoma elasticum (PXE) is a genetic disease that causes mineralization of elastic fibers in some tissues. The most common problems arise in the skin and eyes, and later in blood vessels in the form of premature atherosclerosis. [2] [3] [4] PXE is caused by autosomal recessive mutations in the ABCC6 gene on the short arm of chromosome 16 ...
Pseudoexfoliation syndrome, often abbreviated as PEX [1] and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers. [2] Its cause is unknown, although there is speculation that there may be a genetic ...
Angioid streaks are often associated with pseudoxanthoma elasticum, but have been found to occur in conjunction with other disorders, including Paget's disease, sickle cell disease and Ehlers–Danlos syndrome. These streaks can have a negative impact on vision due to choroidal neovascularization or choroidal rupture.
One is that Mass Eye and Ear is a specialized eye institute that sees a high number of people with rare eye diseases, so the population may have been a little skewed.
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
(H52.2) Astigmatism — the cornea or the lens of the eye is not perfectly spherical, resulting in different focal points in different planes (H52.3) Anisometropia — the lenses of the two eyes have different focal lengths (H52.4) Presbyopia — a condition that occurs with growing age and results in the inability to focus on close objects
The eye develops in utero during the first three months of pregnancy, and a gap called the choroidal fissure appears at the bottom of the stalks that eventually form the eye, the AAO explains.
The retina specialist’s tests did not reveal any problems with my retina, and the doctor sent me to see a neuro-ophthalmologist to examine the nerves of my eye.