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The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Georgios Nikolaou Papanikolaou (or George Papanicolaou / ˌ p æ p ə ˈ n ɪ k ə l aʊ /; Greek: Γεώργιος Ν. Παπανικολάου [papanikoˈlau]; 13 May 1883 – 19 February 1962) was a Greek physician, zoologist and microscopist who was a pioneer in cytopathology and early cancer detection, and inventor of the pap smear for detection of cervical cancer.
Although most notable for its use in the detection of cervical cancer in the Pap test or Pap smear, it is also used to stain non-gynecological specimen preparations from a variety of bodily secretions and from small needle biopsies of organs and tissues. [4] [5] Papanicolaou published three formulations of this stain in 1942, 1954, and 1960. [2]
Andromachi "Mary" Mavrogeni Papanikolaou [note 1] (1890-13 October 1982) was a Greek laboratory technician and the wife of Georgios Papanikolaou, the Greek pathologist who independently invented the pap test. For 21 years, Mary Papanikolaou volunteered to have her cervix sampled and smeared by her husband to help with his efforts to create the ...
Papanikolaou or Papanicolaou (Greek: Παπανικολάου) is a Greek patronymic surname, meaning "child of Father Nikolaos", used in Greece and Cyprus. It may refer to: People
The most common investigation in this field is the Pap test, which is used to screen for potentially precancerous lesions of the cervix. Cytology can also be used to investigate disorders of the ovaries, uterus, vagina and vulva. Gynaecologic cytology makes frequent use of the Bethesda system in order to grade the results of HPV testing. [2]
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The disorder is rare and generally has no symptoms. [2] VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear). [2] Like cervical intraepithelial neoplasia, VAIN comes in three stages, VAIN 1, 2, and 3. [3]
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