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For example, probiotics—which are usually sold in the vitamin aisle—sometimes require refrigeration. Also, capsules that contain liquid or oil may deteriorate more quickly than those that don ...
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
[2] [4] Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. [5] Vitamin B 12 is the most chemically complex of all vitamins, [6] and for humans the only vitamin that must be sourced from animal-derived foods or supplements. [2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8]
Vegans, and to a lesser degree vegetarians, are at risk for B 12 deficiency if they do not consume either a dietary supplement or vitamin-fortified foods. Children are at a higher risk for B 12 deficiency due to inadequate dietary intake, as they have fewer vitamin stores and a relatively larger vitamin need per calorie of food intake. [136]
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The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.