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Gravity affects blood pressure via hydrostatic forces (e.g., during standing), and valves in veins, breathing, and pumping from contraction of skeletal muscles also influence blood pressure in veins. [32] The relationship between pressure, flow, and resistance is expressed in the following equation: [12]
Although the above relationship is true for the hemodynamic factors that determine the flow of blood from the veins back to the heart, it is important not to lose sight of the fact that blood flow through the entire systemic circulation represents both the cardiac output and the venous return, which are equal in the steady-state because the ...
The classic definition by MP Spencer and AB Denison of compliance is the change in arterial blood volume due to a given change in arterial blood pressure ().They wrote this in the "Handbook of Physiology" in 1963 in work entitled "Pulsatile Flow in the Vascular System".
The rate at which fluid is filtered across vascular endothelium (transendothelial filtration) is determined by the sum of two outward forces, capillary pressure and colloid osmotic pressure beneath the endothelial glycocalyx (), and two absorptive forces, plasma protein osmotic pressure and interstitial pressure (). The Starling equation is the ...
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance.
Mean arterial pressure in relation to systolic and diastolic pressure in blood vessels. While MAP can only be measured directly by invasive monitoring, it can be estimated by using a formula in which the lower (diastolic) blood pressure is doubled and added to the higher (systolic) blood pressure and that composite sum then is divided by 3 to estimate MAP.
A blood volume increase would cause a shift along the line to the right, which increases left ventricular end diastolic volume (x axis), and therefore also increases stroke volume (y axis). The Frank–Starling law of the heart (also known as Starling's law and the Frank–Starling mechanism ) represents the relationship between stroke volume ...
Jean Louis Marie Poiseuille is credited with developing the theory of Poiseuille's Flow. It describes the relationship between flow and pressure gradient in long tubes with constant cross section. [2] Otto Frank published the "Fundamental form of the arterial pulse," which contained his "Windkessel theory" of circulation in 1890.