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The most common abnormality the test can screen is trisomy 21 (Down syndrome).In addition to Down syndrome, the triple and quadruple screens assess risk for fetal trisomy 18 also known as Edwards syndrome, open neural tube defects, and may also detect an increased risk of Turner syndrome, triploidy, trisomy 16 mosaicism, fetal death, Smith–Lemli–Opitz syndrome, and steroid sulfatase ...
Abnormally elevated AFP in the serum of a pregnant woman can have one or more of these sources: [citation needed] a problem with the fetus; a problem with the placenta; a tumor or liver disease in the woman; a normally elevated AFP in the fetus or woman (some people naturally have very high AFP)
Of special concern is the secretion of alpha-fetoprotein (AFP); under some circumstances, AFP can be used as a diagnostic marker specific for the presence of yolk sac cells within the teratoma. These cells can develop into a frankly malignant tumor known as yolk sac tumor or endodermal sinus tumor.
Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein [5] [6] that in humans is encoded by the AFP gene. [ 7 ] [ 8 ] The AFP gene is located on the q arm of chromosome 4 (4q13.3). [ 9 ]
Association of Fastpitch Professionals (AFP) is a professional women's fastpitch softball league in the United States consisting of independent teams in collaboration to create a platform for competition at the highest level. The new league began its promotional campaign in 2023 and launched its first official season to begin June, 19 2024.
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In most of the families reported so far, tetra-amelia syndrome appears to have an autosomal recessive pattern of inheritance. [ 1 ] [ 2 ] This means the defective gene responsible for the disorder is located on an autosome , and two copies of the defective gene (one inherited from each parent) are required in order to be born with the disorder.
AFP had a staff of 116 employees in September 2012, [26] and the next year it had chapters in 34 states and reported a membership of 2.3 million. [3] In June 2014, it had 240 employees in 32 states. [27] AFP has been active in national, state, [3] [28] [29] and local elections. [30] [31] AFP registered to lobby in 2014. [32]