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But the truth is men develop breast cancer, too. Men make up about 1% of all breast cancer cases, which means 1 in 726 men will be diagnosed in their lifetimes. The diagnosis is rare in men, but ...
Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.
By attaching a chemotherapy drug to an antibody, doctors are able to deliver more potent cancer-fighting medicines directly into tumor cells, all while causing fewer side effects.. The ...
As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA repair. Upregulation of these genes can overcome the DNA damage and prevent the induction of apoptosis.
For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone. Besides chemotherapy, medical oncology ( pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy).
Palliative chemotherapy is used to control (but not cure) the cancer in settings in which the cancer has spread beyond the breast and localized lymph nodes. See metastatic breast cancer. Combined therapies These combine, for example, non-drug treatments with localized chemotherapy to limit toxicity and achieve better results. [3]
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