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The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV
Epstein Barr Virus (EBV) causes the illness referred to as Mononucleosis. In the infectious stage of this illness, individuals will have Epstein Barr viral capsid antigens (EBV-VCA) in their mouth and blood. [1] [2] The viral capsid of a virus is the complex of proteins that surrounds the genetic material inside the virus. Epstein Barr virus ...
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
Heterophile antibodies are IgM antibodies with affinity for sheep and horse red blood cells. They appear during the first week of infectious mononucleosis symptoms, 3–4 weeks after infection and return to undetectable levels 3 to 6 months after infection. Heterophile antibody is a fairly specific but insensitive test for EBV.
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
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Mononucleosis – Fingerstick testing can be used to test for mononucleosis. Hemoglobin levels – Fingerstick testing of hemoglobin is a quick screening procedure to ensure a blood or plasma donor has an acceptably high blood count for donating blood or blood components .
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