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Prevention of peptic ulcer disease for those who are taking NSAIDs (with low cardiovascular risk) can be achieved by adding a proton pump inhibitor (PPI), an H2 antagonist, or misoprostol. [15] NSAIDs of the COX-2 inhibitors type may reduce the rate of ulcers when compared to non-selective NSAIDs. [15]
Colonization with H. pylori does not always lead to disease, but is associated with a number of stomach diseases. [32] Testing is recommended in cases of peptic ulcer disease or low-grade gastric MALT lymphoma ; after endoscopic resection of early gastric cancer ; for first-degree relatives with gastric cancer, and in certain cases of indigestion.
Upper digestive system diseases 3.8: 0.52%: −21.6 Peptic ulcer disease: 3.1: ... Deaths: Leading Causes for 2009 by the Centers for Disease Control and Prevention;
Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion.
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary ...
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Turck feeds dogs Bacillus coli and produces ulcers. [7] 1907 Berkley Moynihan suggests that acid is a cause of ulcers. [1] 1910 Schwartz publishes the excess acid theory of the ulcer, coining the famous phrase "no acid, no ulcer." [2] Gibelli claims to be unable to reproduce Turck's study where he artificially created ulcers by feeding dogs ...
Differential diagnoses for functional dyspepsia include gastro-oesophageal reflux disease, medication side effects, chronic mesenteric ischemia, symptomatic gallstone disease, sphincter of Oddi dysfunction, biliary dyskinesia, or gallbladder cancer, Crohn's disease, peptic ulcer disease (and infection with Helicobacter pylori), infiltrative ...