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Prepubertal hypertrichosis is characterized by an excess of hair growth, seen during birth and progressing during childhood. [3] [6] In generalized hypertrichosis, excessive hair growth occurs all over the body, whereas in localized hypertrichosis, excessive hair growth only occurs in certain areas of the body. [2]
Hypertrichosis (better known as Werewolf Syndrome) is an abnormal amount of hair growth over the body. [1] [2] The two distinct types of hypertrichosis are generalized hypertrichosis, which occurs over the entire body, and localized hypertrichosis, which is restricted to a certain area. [1]
Uncombable hair syndrome (UHS) is a rare structural anomaly of the hair with a variable degree of effect. It is characterized by hair that is silvery, dry, frizzy, wiry, and impossible to comb. [4] It was first reported in the early 20th century. [5] It typically becomes apparent between the ages of 3 months and 12 years. [6]
The genetic cause of ED lies in mutations, or changes, in certain genes that play an essential role in forming ectodermal structures. These genes are part of signalling pathways—most notably, the EDA/NF-kappaB pathway—which guide the development of hair, skin, nails, teeth, and glands during embryonic growth.
X-linked hypertrichosis was first mapped in chromosome Xq24-q27.1 in a Mexican family; however, the underlying genetic facts remain unknown. [4] X-linked hypertrichosis is inherited in an X-linked dominant pattern of inheritance.
2. Vitamin B12. One of eight B-complex vitamins, vitamin B12 is found naturally in some types of fish, red meat and fortified foods.It plays a key role in central nervous system function, DNA ...
[101] [102] In 2008, researchers at the University of Bonn announced they have found the genetic basis of two distinct forms of inherited hair loss. They found the gene P2RY5 causes a rare, inherited form of hair loss called hypotrichosis simplex. It is the first receptor in humans known to play a role in hair growth.
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