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For a fully oriented molecule, the dipolar coupling for an 1 H-15 N amide group would be over 20 kHz, and a pair of protons separated by 5 Å would have up to ~1 kHz coupling. However the degree of alignment achieved by applying magnetic field is so low that the largest 1 H-15 N or 1 H-13 C dipolar couplings are <5 Hz. [19]
Magnetic dipole–dipole interaction, also called dipolar coupling, refers to the direct interaction between two magnetic dipoles. Roughly speaking, the magnetic field of a dipole goes as the inverse cube of the distance, and the force of its magnetic field on another dipole goes as the first derivative of the magnetic field. It follows that ...
The mechanisms of nuclear-spin energy-coupling have been extensively characterized and are described in the following articles: Angular momentum coupling, Magnetic dipole–dipole interaction, J-coupling, Residual dipolar coupling, Nuclear Overhauser effect, Spin–spin relaxation, and Spin saturation transfer. Alternatively, some nuclei in a ...
It is believed that motor skill acquisition requires learning a new internal model of limb dynamics. [ 4 ] [ 5 ] For instance, in order to reach for a cup of coffee, a person must have an implicit understanding of the mass of their own arm, and how specific patterns of muscle activation will change the position of that limb.
Other authors suggest a new notion of the phylogenetic and ontogenetic origin of action understanding that utilizes the motor system; the motor cognition hypothesis. This states that motor cognition provides both human and nonhuman primates with a direct, prereflexive understanding of biological actions that match their own action catalog. [5]
The goal of motor skill is to optimize the ability to perform the skill at the rate of success, precision, and to reduce the energy consumption required for performance. Performance is an act of executing a motor skill or task. Continuous practice of a specific motor skill will result in a greatly improved performance, which leads to motor ...
During motor learning, the forward and inverse models are paired and tightly coupled by a responsibility signal within modules. Using the forward model's predictions and sensory contextual cues, responsibility signals indicate the degree to which each pair should be responsible for controlling current behavior.
Motor adaptation is a robust phenomenon and was also found in monkeys [8] and mice [9] performing motor tasks. Using optogenetics the study, done by Dr. Mackenzie Mathis at Harvard University, using mice could also show that somatosensory cortex is involved in updating the internal model.