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Melatonin appears to cause very few side effects as tested in the short term, up to three months, at low doses. [ clarification needed ] [ dubious – discuss ] Two systematic reviews found no adverse effects of exogenous melatonin in several clinical trials, and comparative trials found the adverse effects headaches, dizziness, nausea, and ...
The popular sleep aid can have side effects.
Study up on the major pros and cons of popping this supplement in an attempt to sleep more soundly.
Melatonin supplements for sleep come with side effects and their use may raise safety concerns, experts say. There's little evidence they help with insomnia.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Usage of melatonin as a treatment for insomnia in adults has increased from 0.4% between 1999 and 2000 to nearly 2.1% between 2017 and 2018. [164] While the use of melatonin in the short-term has been proven to be generally safe and it is shown to not be a dependent medication, side effects can still occur. [165]