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The World Health Organization (WHO) does not recommend the use of combined oral contraceptive pills in women with breast cancer. [41] [97] Since combined oral contraceptive pills contain both estrogen and progestin, they are not recommended to be used in those with hormonally-sensitive cancers, including some types of breast cancer.
Between 2015 and 2017, 64.9% of women ages 15–49 in the United States were using contraception, and of those 12.6% were using the oral contraceptive pill. [46] There are approximately 100 million users of combined oral contraceptives worldwide, with use being more common in Western Europe, Northern Europe, and the United States. [47]
Progestogen-only pills (POPs), colloquially known as "mini pills", are a type of oral contraceptive that contain synthetic progestogens and do not contain estrogens. [4] They are primarily used for the prevention of undesired pregnancy, although additional medical uses also exist.
As of June 2018, it is in phase II clinical trials for breast cancer and prostate cancer. [citation needed] In addition to a single-drug formulation, estetrol is being developed in combination with the progestin drospirenone for hormonal contraception (use as a birth control pill) to prevent pregnancy.
Progestins in birth control pills are sometimes grouped by generation. [ 239 ] [ 240 ] While the 19-nortestosterone progestins are consistently grouped into generations, the pregnane progestins that are or have been used in birth control pills are typically omitted from such classifications or are grouped simply as "miscellaneous" or "pregnanes".
Trials have shown that the drug reduces breast cancer cases by 49 per cent over 11 years among eligible women, meaning that if just 25 per cent of eligible women in England take up the offer ...
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