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Dicamba is toxic to conifer species but is in general less toxic to grasses. [2] Dicamba is a synthetic auxin that functions by increasing plant growth rate, leading to senescence and cell death. [2] [11] The growth regulating properties of dicamba were first discovered by Zimmerman and Hitchcock in 1942. [12]
Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Arteries deliver oxygenated blood, glucose and other nutrients to the brain.
The blood–brain barrier is formed by the brain capillary endothelium and excludes from the brain 100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. [28] Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders.
The cells of the neurovascular unit also make up the blood–brain barrier (BBB), which plays an important role in maintaining the microenvironment of the brain. [11] In addition to regulating the exit and entrance of blood, the blood–brain barrier also filters toxins that may cause inflammation, injury, and disease. [12]
Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier into the brain.This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier.
Carbs get a bad reputation. The popularity of low-carb diets has led many people to limit them or cut out carbs altogether. But carbs are actually great brain food—when you choose the right ones.
Brain trauma or stroke can cause ischemia, in which blood flow is reduced to inadequate levels. Ischemia is followed by accumulation of glutamate and aspartate in the extracellular fluid , causing cell death, which is aggravated by lack of oxygen and glucose .
Here's another reason to eat better in 2017: a new study finds it's good for your brain health and memory.