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Sir John Bertrand Gurdon FRS (born 2 October 1933) is a British developmental biologist, best known for his pioneering research in nuclear transplantation [2] [3] [4] and cloning. [ 1 ] [ 5 ] [ 6 ] [ 7 ]
In particular, the research of Sir John Gurdon in 1958 entailed the cloning of Xenopus laevis utilizing the principles of SCNT. [5] In short, the experiment consisted of inducing a female specimen to ovulate, at which point her eggs were harvested. From here, the egg was enucleated using ultra-violet irradiation to disable the egg's pronucleus.
The first direct experimental examination of the ability of nuclear proteins to accumulate in the nucleus was carried out by John Gurdon when he showed that purified nuclear proteins accumulate in the nucleus of frog oocytes after being micro-injected into the cytoplasm. These experiments were part of a series that subsequently led to studies ...
The first vertebrate ever to be cloned was an African clawed frog in 1962, [35] an experiment for which Sir John Gurdon was awarded the Nobel Prize in Physiology or Medicine in 2012 "for the discovery that mature cells can be reprogrammed to become pluripotent". [36]
In 1962, John B. Gurdon demonstrated that the nucleus from a differentiated frog intestinal epithelial cell can generate a fully functional tadpole via transplantation to an enucleated egg. Gurdon used somatic cell nuclear transfer (SCNT) as a method to understand reprogramming and how cells change in specialization. He concluded that ...
Ellen Greenberg was found dead in 2011 in her Philadelphia apartment with 20 knife wounds and numerous bruises. Authorities ruled her death a suicide. Fourteen years later, the pathologist who ...
A last-minute glitch surfaced on Thursday in the details of the Gaza ceasefire-for-hostages deal and U.S. envoys are working to resolve it, a U.S. official said. Working on the issue is President ...
Watch the Video. Click here to watch on YouTube. The ostrich is quite an unusual animal. With its giant feathery plumes, massive feet, and long spindly legs, it looks like something right out of a ...