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Myofascial pain syndrome is a focal hyperirritability in muscle that can strongly modulate central nervous system functions. Scholars distinguish this from fibromyalgia, which is characterized by widespread pain and tenderness and is described as a central augmentation of nociception giving rise to deep tissue tenderness that includes muscles ...
Localized muscle pain; Trigger points that activate the pain (MTrPs) Generally speaking, the muscular pain is steady, aching, and deep. Depending on the case and location the intensity can range from mild discomfort to excruciating and "lightning-like". Knots may be visible or felt beneath the skin.
The pathogenesis of dermatomyositis involves an autoimmune-mediated process characterized by immune complex deposition and complement activation, leading to microangiopathy in both muscle and skin tissues. The specific mechanism of tissue injury is variable, depending on the specific autoantibodies and immune cell types involved. [16]
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C. tetani is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin, such as a cut or puncture wound caused by a contaminated object. [1] [3] They produce toxins that interfere with normal muscle contractions. [4] Diagnosis is based on the presenting signs and symptoms.
Induration (hardening of the skin and soft tissue) Excessive pain; Systemic symptoms, including high fever > 102 °F, fatigue, muscle pains [7] Large amounts of smelly pus and discharge, especially at a surgical site [3] The initial skin changes are similar to cellulitis or abscess, so diagnosis in early stages may be difficult. The redness and ...
Gas gangrene can cause myonecrosis (muscle tissue death), gas production, and sepsis. Progression to toxemia and shock is often very rapid. It can easily be noticed by the large, blackened sores that form, as well as a degree of loud and distinctive crepitus caused by gas escaping the necrotic tissue.