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  2. Retinal pigment epithelium - Wikipedia

    en.wikipedia.org/wiki/Retinal_pigment_epithelium

    The RPE was known in the 18th and 19th centuries as the pigmentum nigrum, referring to the observation that the RPE is dark (black in many animals, brown in humans); and as the tapetum nigrum, referring to the observation that in animals with a tapetum lucidum, in the region of the tapetum lucidum the RPE is not pigmented. [3]

  3. Congenital hypertrophy of the retinal pigment epithelium

    en.wikipedia.org/wiki/Congenital_hypertrophy_of...

    Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a harmless, pigmented fundus lesion that can be of various forms: solitary, grouped, and atypical, [1] and are found through clinical eye screenings from digital retinal imaging often established by ophthalmologists. [2]

  4. Drusen - Wikipedia

    en.wikipedia.org/wiki/Drusen

    Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1]

  5. White dot syndromes - Wikipedia

    en.wikipedia.org/wiki/White_dot_syndromes

    Multifocal choroiditis occurs mainly in myopic females. The fundus presents with yellow or gray lesions (white dots) at the level of the choroid and retinal pigment epithelium. The size of the white dots are between 50 and 500 micrometres and localized in the macula. The disease is characterized by vitritis and anterior chamber inflammation.

  6. RPE65 - Wikipedia

    en.wikipedia.org/wiki/RPE65

    Retinal pigment epithelium-specific 65 kDa protein (also known as RPE65) is a retinoid isomerohydrolase enzyme of the vertebrate visual cycle. [5] [6] RPE65 is expressed in the retinal pigment epithelium (RPE, a layer of epithelial cells that nourish the photoreceptor cells) and is responsible for the conversion of all-trans-retinyl esters to 11-cis-retinol during phototransduction.

  7. Cone dystrophy - Wikipedia

    en.wikipedia.org/wiki/Cone_dystrophy

    Cone dystrophy; Fundus of a 45 year-old patient with cone rod dystrophy segregating with a loss-of-function mutation (E1087X) in ABCA4. Note the presence of various-shaped pigment deposits in the posterior pole with atrophy of the retina, while the retina appears less damaged in periphery (upper part of the photograph).

  8. Dilated fundus examination - Wikipedia

    en.wikipedia.org/wiki/Dilated_fundus_examination

    Dilated fundus examination (DFE) is a diagnostic procedure that uses mydriatic eye drops to dilate or enlarge the pupil in order to obtain a better view of the fundus of the eye. [1] Once the pupil is dilated, examiners use ophthalmoscopy to view the eye's interior, which makes it easier to assess the retina , optic nerve head , blood vessels ...

  9. Acute posterior multifocal placoid pigment epitheliopathy

    en.wikipedia.org/wiki/Acute_posterior_multifocal...

    Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired inflammatory uveitis that belongs to the heterogenous group of white dot syndromes in which light-coloured (yellowish-white) lesions begin to form in the macular area of the retina.