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Congenital TEF can arise due to failed fusion of the tracheoesophageal ridges after the fourth week of embryological development. [4] A fistula, from the Latin meaning 'a pipe', is an abnormal connection running either between two tubes or between a tube and a surface. In tracheo-esophageal fistula it runs between the trachea and the esophagus.
T - Tracheoesophageal fistula; E - Esophageal atresia; R - Renal (Kidney) and/or radial anomalies; L - Limb defects; Although it was not conclusive whether VACTERL should be defined by at least two or three component defects, [4] it is typically defined by the presence of at least three of the above congenital malformations. [5]
TEF (tracheoesophageal fistula) ONLY with no Esophageal Atresia, H-Type Esophagus fully intact and capable of its normal functions, however, there is an abnormal connection between the esophagus and the trachea.
Twenty to 27% of individuals with a laryngeal cleft also have a tracheoesophageal fistula and approximately 6% of individuals with a fistula also have a cleft. [4] Other congenital anomalies commonly associated with laryngeal cleft are gastro-oesophageal reflux, tracheobronchomalacia, congenital heart defect, dextrocardia and situs inversus. [5]
A tracheo-esophageal puncture (or tracheoesophageal puncture) is a surgically created hole between the trachea (windpipe) and the esophagus (food pipe) in a person who has had a total laryngectomy, a surgery where the larynx (voice box) is removed. The purpose of the puncture is to restore a person’s ability to speak after the vocal cords ...
Esophageal atresia with or without tracheoesophageal fistula (TEF) is the most common birth defect of the esophagus. The diagnosis of EA usually occurs within the first 24 hours of life, but it can be made antenatally or later. [8] Although environmental effects and genetic factors have been documented, the causes of EA remain largely unknown. [9]
Incidence of congenital malformations associated with tracheal agenesis. Results were obtained from a total of 32 individual case studies. [11]The classic in-utero symptoms of tracheal agenesis are an absence of the trachea leading to congenital high airway obstruction syndrome, [12] [13] lung distention, polyhydramnios, heart malformations, heart displacement and hydrops fetalis.
Imperforate anus is usually present along with other birth defects—spinal problems, heart problems, tracheoesophageal fistula, esophageal atresia, renal anomalies and limb anomalies are among the possibilities, collectively being called the VACTERL association. [8]