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  2. Propofol - Wikipedia

    en.wikipedia.org/wiki/Propofol

    One of propofol's most common side effects is pain on injection, especially in smaller veins. This pain arises from activation of the pain receptor, TRPA1, [54] found on sensory nerves and can be mitigated by pretreatment with lidocaine. [55] Less pain is experienced when infused at a slower rate in a large vein (antecubital fossa).

  3. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    The prosuicidal effects of benzodiazepines are suspected to be due to a psychiatric disturbance caused by side effects or withdrawal symptoms. [11] Because benzodiazepines in general may be associated with increased suicide risk, care should be taken when prescribing, especially to at-risk patients.

  4. GABAA receptor positive allosteric modulator - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor_positive...

    At first benzodiazepines were considered to be safe and efficient minor tranquilizers but then were criticized for their dependence producing effects. Several efficient benzodiazepines offer choices about dosage form , length of action, metabolic interaction and safety.

  5. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels ...

  6. Phenazepam - Wikipedia

    en.wikipedia.org/wiki/Phenazepam

    Side effects [ edit ] As with other benzodiazepines, in case of abrupt discontinuation following prolonged use, severe withdrawal symptoms may occur including restlessness , anxiety , insomnia , seizures , convulsions and death , though because of its intermediate half-life [ 17 ] [ 18 ] [ 19 ] as well as that of its active metabolites, these ...

  7. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    [87] [108] Less common side effects include nausea and changes in appetite, blurred vision, confusion, euphoria, depersonalization and nightmares. Cases of liver toxicity have been described but are very rare. [24]: 183–189 [112] The long-term effects of benzodiazepine use can include cognitive impairment as well as affective and behavioural ...

  8. Serious Ozempic Side Effects, Confirmed: Here’s What to Know

    www.aol.com/serious-ozempic-side-effects...

    A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.

  9. Paradoxical reaction - Wikipedia

    en.wikipedia.org/wiki/Paradoxical_reaction

    Paradoxical effects of benzodiazepines appear to be dose-related, that is, likelier to occur with higher doses. [ 16 ] In a letter to the British Medical Journal , it was reported that a high proportion of parents referred for actual or threatened child abuse were taking medication at the time, often a combination of benzodiazepines and ...

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