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Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2]
Those with autoimmune atrophic gastritis (Type A gastritis) are statistically more likely to develop gastric carcinoma (a form of stomach cancer), Hashimoto's thyroiditis, and achlorhydria. Type A gastritis primarily affects the fundus (body) of the stomach and is more common with pernicious anemia . [ 1 ]
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Megaloblastic anemia (MA) is associated with GSE and is believed to be the result of B 12 and folate deficiency. [23] In GSE, it appears to be associated with the IgA-less phenotype. [24] Unlike other forms of megaloblastic anemia, GSEA MA is not a form of autoimmune gastritis. [25] Pernicious anemia (PA).
Condition name ICD-10 coding number Diseases Database coding number Medical Subject Headings Iron-deficiency anemia: D50: 6947: Iron-deficiency anemia (or iron deficiency anaemia) is a common anemia that occurs when iron loss (often from intestinal bleeding or menses) occurs, and/or the dietary intake or absorption of iron is insufficient.
Some of the most common diseases that are generally categorized as autoimmune include coeliac disease, type 1 diabetes, Graves' disease, inflammatory bowel diseases (such as Crohn's disease and ulcerative colitis), multiple sclerosis, alopecia areata, [9] Addison's disease, pernicious anemia, psoriasis, rheumatoid arthritis, and systemic lupus ...
Age-related macular degeneration: AML Acute myelogenous leukemia: AN Anorexia nervosa: AOCD Anemia of chronic disease: AODM Adult onset diabetes mellitus: AOS Apraxia of speech: APA Aldosterone-producing adenoma: APS Antiphospholipid syndrome: ARBD Alcohol-related birth defects: ARD Adult Refsum disease: ARDS Acute respiratory distress syndrome ...
Treatment of gastritis that leads to pernicious anemia consists of parenteral vitamin B-12 injection. Associated immune-mediated conditions (e.g., insulin-dependent diabetes mellitus, autoimmune thyroiditis) should also be treated. However, treatment of these disorders has no known effect in the treatment of achlorhydria.