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Amisulpride is approved and used at low doses in the treatment of dysthymia and major depressive disorder. [10] [20] [11] [21] [22] [23] Whereas typical doses used in schizophrenia block postsynaptic dopamine D 2-like receptors and reduce dopaminergic neurotransmission, low doses of amisulpride preferentially block presynaptic dopamine D 2 and D 3 autoreceptors and thereby disinhibit dopamine ...
Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs . It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used in traditional Chinese medicine .
Common side effects include diarrhea, vomiting, bone marrow suppression, hair loss, shortness of breath, and fever. [8] Other severe side effects include blood clots, colon inflammation, and allergic reactions. [8] Those with two copies of the UGT1A1*28 gene variant are at higher risk for side effects. [8]
Viagra (Sildenafil): Uses, Benefits and Side Effects. This article was reviewed by Kelly Brown MD, MBA.. Whether you’re a senior in high school or a senior-living resident, you’ve likely heard ...
Common side effects include headache, dizziness, feeling tired, and intestinal upset. [3] Serious side effects may include angioedema, gallstones, liver problems, and muscle breakdown. [3] Use in pregnancy and breastfeeding is of unclear safety. [5] It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids ...
Adverse effects occur in fewer than 1% of patients and include muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia, and dry mouth. All effects are reversible. [3] [4] Allergic reactions occur in fewer than 0.1% of patient and include skin rash, hives, Quincke's edema, and in some cases anaphylactic shock. [3] [7] [8] [9]
The U.S. Department of Health & Human Services may seek over $1 billion from Johnson & Johnson as reimbursement for federal health agencies' payments of medical costs for patients who allege that ...
Other side effects of gold-containing drugs include kidney damage, itching rash, and ulcerations of the mouth, tongue, and pharynx. Approximately 35% of patients discontinue the use of gold salts because of these side effects. Kidney function must be monitored continuously while taking gold compounds. [5]