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The heat shock response (HSR) is a cell stress response that increases the number of molecular chaperones to combat the negative effects on proteins caused by stressors such as increased temperatures, oxidative stress, and heavy metals. [1]
An HSR is one type of change in a chromosome's structure which is frequently observed in the nucleus of human cancer cells. In the region of a chromosome where an HSR occurs, a segment of the chromosome, which presumably contains a gene or genes that give selective advantage to the progression of the cancer, is amplified or duplicated many times.
High-Speed Research Program, a 1990–1999 NASA supersonic jet program; Hisar Junction railway station, in Haryana, India; Historic Sportscar Racing, an American historic motorsport series; Holyoke Street Railway, a former transit system in western Massachusetts; Hot Springs Municipal Airport, South Dakota, US; Mitsubishi HSR, a concept car
Health services research (HSR) became a burgeoning field in North America in the 1960s, when scientific information and policy deliberation began to coalesce. [1] Sometimes also referred to as health systems research or health policy and systems research (HPSR), HSR is a multidisciplinary scientific field that examines how people get access to health care practitioners and health care services ...
SciELO is a bibliographic database and a model for cooperative electronic publishing in developing countries originally from Brazil. It contains 985 scientific journals from different countries in free and universal access, full-text format. Free FAPESP, CNPq and BIREME: Science.gov: Multidisciplinary
The developmentally active and heat shock inducible hsromega or hsrω gene in Drosophila produces multiple long non-coding RNA transcripts.This gene is transcriptionally active in almost all cell types of Drosophila and is the most actively induced following heat shock.
A research design that involves multiple measures of the same variable taken on the same or matched subjects either under different conditions or over two or more time periods. [ 1 ] Paired t-test , Wilcoxon signed-rank test
Aside from these models, several studies suggest other processes for DM formation such as through the breakdown of a homogeneously staining region (HSR) following cell fusion, [5] through chromosomal breaks due to hypoxia induced activation of fragile sites, [6] or reduction in the level of DNA methylation.