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Omphalitis of newborn is the medical term for inflammation of the umbilical cord stump in the neonatal newborn period, most commonly attributed to a bacterial infection. [1] Typically immediately after an infant is born, the umbilical cord is cut with a small remnant (often referred to as the stump) left behind.
The youngest and most primitive MSCs may be obtained from umbilical cord tissue, namely Wharton's jelly and the umbilical cord blood. However, MSCs are found in much higher concentration in the Wharton's jelly compared to cord blood, which is a rich source of hematopoietic stem cells. The umbilical cord is available after a birth.
Neonatal sepsis of the newborn is an infection that has spread through the entire body. The inflammatory response to this systematic infection can be as serious as the infection itself. [ 26 ] In infants that weigh under 1500 g, sepsis is the most common cause of death.
Umbilical granuloma is the most common umbilical abnormality in newborn children or neonates, causing inflammation and drainage. [1] [2] [3] It may appear in the first few weeks of newborn infants during the healing process of the umbilical cord due to an umbilical mass. [4] It is the overgrowth of the umbilical tissue. [5]
Neonatal tetanus (trismus nascentium) is a form of generalised tetanus that occurs in newborns. Infants who have not acquired passive immunity from an immunized mother are at risk. It usually occurs through infection of the unhealed umbilical stump, particularly when the stump is cut with a non-sterile instrument.
Wharton's jelly (substantia gelatinea funiculi umbilicalis) is a gelatinous substance within the umbilical cord, [1] largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It acts as a mucous connective tissue containing some fibroblasts and macrophages , and is derived from extra-embryonic mesoderm of the connecting ...
A newborn was rescued in Syria after her mother reportedly gave birth and became trapped in rubble following a devastating 7.8-magnitude earthquake.
The embryo is surrounded by the thin membranes of the amniotic sac, the umbilical cord is seen in the center, attaching the embryo to the placenta. The umbilical cord develops from and contains remnants of the yolk sac and allantois. It forms by the fifth week of development, replacing the yolk sac as the source of nutrients for the embryo. [2]