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This presents with the classical triad of ataxia, areflexia and ophthalmoplegia. The clinical spectrum of disorders associated with anti-GQ1b now is also recognized to include, Bickerstaff brainstem encephalitis, Guillain-Barré syndrome with ophthalmoplegia, and acute ophthalmoplegia without ataxia. [11]
Anti-GQ1b antibodies have been found in two-thirds of patients with this condition. [7] This antibody is also found in almost all cases of Miller Fisher syndrome. The EEG is often abnormal, but shows only slow wave activity, which also occurs in many other conditions, and so is of limited value in diagnosis.
These antibodies are present in the branch of CIDP diseases comprised by anti-GM1, anti-GD1a, and anti-GQ1b. Sural nerve biopsy ; biopsy is considered for those patients in whom the diagnosis is not completely clear, when other causes of neuropathy (e.g., hereditary, vasculitic) cannot be excluded, or when profound axonal involvement is ...
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
2023 US News & World Report rankings for Mayo Clinic Jacksonville [11] Specialty Rank (In the U.S.) Score (Out of 100) Cancer #27 68.8 Cardiology #29 65.7
Robert A. Kyle is a professor of medicine, Laboratory Medicine and Pathology at the Mayo Clinic.He specializes in the care of patients with plasma cell dyscrasias. . Throughout his career Kyle has published more than 1,850 scientific papers and abstracts on myeloma and other plasma cell diso
Eagle syndrome (also termed stylohyoid syndrome, [1] styloid syndrome, [2] stylalgia, [3] styloid-stylohyoid syndrome, [2] or styloid–carotid artery syndrome) [4] is an uncommon condition commonly characterized but not limited to sudden, sharp nerve-like pain in the jaw bone and joint, back of the throat, and base of the tongue, triggered by swallowing, moving the jaw, or turning the neck. [1]