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Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing [ 42 ] [ 43 ] and initiated a series of improvements in pregnancy testing leading to the contemporary at-home testing. [ 43 ]
Clearblue home pregnancy test system 1985. Clearblue was introduced in 1985 with the launch of the first Clearblue Home Pregnancy Test system, which at the time was owned by Unilever. [4] It was the world’s first “rapid home test” that gave pregnancy test results in 30 minutes and allowed a woman to take a test before going to the doctor. [4]
Primodos was a hormone-based pregnancy test, produced by Schering AG, and used in the 1960s and 1970s that consisted of two pills that contained norethisterone (as acetate) and ethinylestradiol. [ 1 ] [ 2 ] It detected pregnancy by inducing menstruation in women who were not pregnant.
Before immunological pregnancy tests were developed in the 1960s, women relied on urine-based pregnancy tests using animals, ranging from mice to frogs. [ 1 ] [ 2 ] Advancements in medical technology have enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home.
A NASA illustration of a lateral flow assay. A lateral flow test (LFT), [1] is an assay also known as a lateral flow immunochromatographic test (ICT), or rapid test.It is a simple device intended to detect the presence of a target substance in a liquid sample without the need for specialized and costly equipment.
Gravindex is an agglutination inhibition test performed on a urine sample to detect pregnancy. [1] It is based on double antigen antibody reaction. The test detects the prevention of agglutination of HCG -coated latex particles by HCG present in the urine of pregnant women.