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Chagas disease is managed using antiparasitic drugs to eliminate T. cruzi from the body, and symptomatic treatment to address the effects of the infection. [6] As of 2018, benznidazole and nifurtimox were the antiparasitic drugs of choice for treating Chagas disease, [2] though benznidazole is the only drug available in most of Latin America. [40]
The Chagas: Time to Treat Campaign is an international campaign started by the Drugs for Neglected Diseases initiative to advocate for increased research and development of treatments for Chagas disease. Chagas is a potentially fatal neglected disease that affects between 8 and 13 million people worldwide. DNDi's Time to Treat campaign is ...
Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...
Doctors, researchers, and patient advocates say the U.S. could be doing far more to combat Chagas, which causes serious heart disease in an estimated 30% of infected people and can also lead to ...
The disease has spread to the U.S. in the last 40 years, says the American Heart Association, but many doctors are unfamiliar with how to diagnose and treat it.
Doctors, researchers, and patient advocates say the U.S. could be doing far more to combat Chagas, which causes serious heart disease in an estimated 30% of infected people and can also lead to ...
Fexinidazole is a medication used to treat African trypanosomiasis (sleeping sickness) caused by Trypanosoma brucei gambiense. [3] It is effective against both first and second stage disease. [3] Also a potential new treatment for Chagas disease, a neglected tropical disease that affects millions of people worldwide. [4] It is taken by mouth. [5]
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2] [4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth. [2]