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As of 2010, as many as 16 genes have been associated with eye color inheritance. Some of the eye-color genes include OCA2 and HERC2. [9] [10] The earlier belief that blue eye color is a recessive trait has been shown to be incorrect, and the genetics of eye color are so complex that almost any parent-child combination of eye colors can occur.
This gene seems to be the main determinant of eye color depending on the amount of melanin production in the iris stroma (large amounts giving rise to brown eyes; little to no melanin giving rise to blue eyes). This gene is mutated in Astyanax mexicanus, a Mexican fish which is characterized by a chronic albinism in cave-dwelling individuals ...
Your eye color is determined by the amount and distribution of melanin in the iris of the eye. And of course, the genes we inherit from our parents play a significant role in determining our eye ...
A phenotypic trait is an obvious, observable, and measurable characteristic of an organism; it is the expression of genes in an observable way. An example of a phenotypic trait is a specific hair color or eye color. Underlying genes, that make up the genotype, determine the hair color, but the hair color observed is the phenotype.
Eye color, specifically the color of the irises, is determined primarily by the concentration and distribution of melanin. Although the processes determining eye color are not fully understood, it is known that inherited eye color is determined by multiple genes. Environmental or acquired factors can alter these inherited traits. [7]
HERC2 is a giant E3 ubiquitin protein ligase, implicated in DNA repair regulation, pigmentation and neurological disorders.It is encoded by a gene of the same name belonging to the HERC family, which typically encodes large protein products with C-terminal HECT domains and one or more RCC1-like (RLD) domains.
The reason boils down to genes. A senior lecturer in biomolecular sciences at Liverpool John Moores University said, "What we know now is that eye color is based on 12 to 13 individual variations ...
Eye color is an inherited trait influenced by more than one gene, including OCA2 and HERC2. The interaction of multiple genes—and the variation in these genes ("alleles") between individuals—help to determine a person's eye color phenotype.