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Megalencephaly (or macrencephaly; abbreviated MEG) is a growth development disorder in which the brain is abnormally large. It is characterized by a brain with an average weight that is 2.5 standard deviations above the mean of the general population. [2]
Abnormal growth; Excessive thirst; Reduced consciousness; Some symptoms in adults are specific to the location of the tumor: Tumors in the cerebrum, which controls movement, may cause weakness or numbness to the body. This weakness is often limited to one side of the body. Tumors in the Broca's area of the cerebrum can cause speech difficulties ...
Pachygyria, lissencephaly (smooth brain), and polymicrogyria (multiple small gyri) are all the results of abnormal cell migration. The abnormal migration is typically associated with a disorganized cellular architecture, failure to form six layers of cortical neurons (a four-layer cortex is common), and functional problems.
Macrocephaly is a condition in which circumference of the human head is abnormally large. [1] It may be pathological or harmless, and can be a familial genetic characteristic. . People diagnosed with macrocephaly will receive further medical tests to determine whether the syndrome is accompanied by particular disorde
Classification of brainstem gliomas by MRI appearance. Histopathology of a brainstem glioma. A brainstem glioma is a cancerous glioma tumor in the brainstem.Around 75% are diagnosed in children and young adults under the age of twenty, but have been known to affect older adults as well. [1]
When a cortical dysplasia is a cause of epilepsy, then seizure medications (anticonvulsants) are a first line treatment. If anticonvulsants fail to control seizure activity, neurosurgery may be an option to remove or disconnect the abnormal cells from the rest of the brain (depending on where the cortical dysplasia is located and the safety of ...
Human growth hormone derived from cadavers was linked to Alzheimer's disease in five patients who received injections decades ago, a study in Nature Medicine finds. ... of plaques and tangles in ...
The cause of polymicrogyria is unclear. It is generally agreed that PMG occurs during late neuronal migration (when majority of the neurons arrived at cerebral cortex after their starting points around the ventricular system of the brain) or early cortical organization of fetal development. Evidence for both genetic and non-genetic causes ...
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