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Lithium orotate (C 5 H 3 LiN 2 O 4) is a salt of orotic acid and lithium.It is available as the monohydrate, LiC 5 H 3 N 2 O 4 ·H 2 O. [1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissolves in solution to produce free lithium ions.
Orotic acid is a Bronsted acid and its conjugate base, the orotate anion, is able to bind to metals. Lithium orotate, for example, has been investigated for use in treating alcoholism, [4] [5] and complexes of cobalt, manganese, nickel, and zinc are known. [6]
They used lithium urate, already known to be the most soluble urate compound, and observed that it caused the rodents to become tranquil. Cade and Andrews traced the effect to the lithium-ion itself, and after Cade ingested lithium himself to ensure its safety in humans, he proposed lithium salts as tranquilizers. He soon succeeded in ...
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3 Orotate? 2 comments. 4 Literature. 1 comment. 5 Legal Issue. 2 comments. 6 Original research section moved from article. 1 comment. 7 Contradiction of toxic levels ...