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Lithium orotate (C 5 H 3 LiN 2 O 4) is a salt of orotic acid and lithium.It is available as the monohydrate, LiC 5 H 3 N 2 O 4 ·H 2 O. [1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissolves in solution to produce free lithium ions.
Orotic acid is a Bronsted acid and its conjugate base, the orotate anion, is able to bind to metals. Lithium orotate, for example, has been investigated for use in treating alcoholism, [4] [5] and complexes of cobalt, manganese, nickel, and zinc are known. [6]
7), lithium sulfate, lithium chloride, and lithium orotate. [ 139 ] [ 140 ] Nanoparticles and microemulsions have also been invented as drug delivery mechanisms. As of 2020, there is a lack of evidence that alternate formulations or salts of lithium would reduce the need for monitoring serum lithium levels or lower systemic toxicity.
ALTO-100, previously known as NSI-189 (NeuralStem Inc. 189), [3] is a drug described as a hippocampal neurogenesis stimulant and indirect brain-derived neurotrophic factor (BDNF) modulator which is under development for the treatment of major depressive disorder (MDD), bipolar depression, and post-traumatic stress disorder (PTSD).
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Tell Me Everything You Don't Remember: The Stroke That Changed My Life is a book by Christine Hyung-Oak Lee, published in 2017. Lee suffered a stroke at the age of 33. She explains her symptoms, realization, hospital experience, and the recovery process of the incident and trauma.
NBC News asked transgender people from across the country to share how their life satisfaction has changed after transition. Out of two dozen respondents, all but one said they feel more joy in ...
Lithium aspartate (C 4 H 6 LiNO 4) is a salt of aspartic acid and lithium.It is sometimes marketed as a dietary supplement used in small doses to treat certain medical conditions; however, there are no systematic reviews supporting the efficacy, or safety of lithium aspartate and it is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition.