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The cavernous sinus is one of the dural venous sinuses of the head. It is a network of veins that sit in a cavity.It sits on both sides of the sphenoidal bone and pituitary gland, approximately 1 × 2 cm in size in an adult. [2]
The cavernous sinus lies within the cranial cavity, between layers of the meninges, and is a major conduit of venous drainage from the brain. [3] Despite this relatively plausible anatomical argument, only severe facial infections (e.g., nasal abscess) can lead to a deeper central nervous system infection complication.
Cavernous sinus thrombosis (CST) is the formation of a blood clot within the cavernous sinus, a cavity at the base of the brain which drains deoxygenated blood from the brain back to the heart. This is a rare disorder and can be of two types–septic cavernous thrombosis and aseptic cavernous thrombosis. [ 1 ]
Right smack in the center of that triangle, although under the surface of the skin, is the cavernous sinus, which houses essential nerves and blood vessels that carry blood back to the brain. If ...
The walls of the dural venous sinuses are composed of dura mater lined with endothelium, a specialized layer of flattened cells found in blood and lymph vessels.They differ from other blood vessels in that they lack a full set of vessel layers (e.g. tunica media) characteristic of arteries and veins.
A carotid-cavernous fistula results from an abnormal communication between the arterial and venous systems within the cavernous sinus in the skull. It is a type of arteriovenous fistula .
The medial angle of the eye, nose and lips (known as the danger triangle of the face) usually drain through the facial vein, via the superior ophthalmic vein through the cavernous sinus. An infection of the face may spread to the cavernous sinus through the superior ophthalmic vein. [6] This can cause cavernous sinus thrombosis. [6]
Cavernous sinus thrombosis is a specialised form of cerebral venous sinus thrombosis, where there is thrombosis of the cavernous sinus of the basal skull dura, due to the retrograde spread of infection and endothelial damage from the danger triangle of the face.