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Taking certain types of medications can contribute to gout. A couple examples include cyclosporine, an immunosuppressant drug, and diuretics. Lastly, dietary factors also increase gout risk.
What causes gout? The condition is caused by a buildup of uric acid in the body. Uric acid forms when the body breaks down purines, a chemical compound that cells use to form DNA and RNA.
Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...
Once the acute attack resolves, levels of uric acid can be lowered via lifestyle changes or allopurinol. [3] Taking vitamin C and eating a diet high in low-fat dairy products may be preventive. [ 7 ]
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Low uric acid (hypouricemia) can have numerous causes. Low dietary zinc intakes cause lower uric acid levels. This effect can be even more pronounced in women taking oral contraceptive medication. [61] Sevelamer, a drug indicated for prevention of hyperphosphataemia in people with chronic kidney failure, can significantly reduce serum uric acid ...