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Interneurons (also called internuncial neurons, association neurons, connector neurons, or intermediate neurons) are neurons that are not specifically motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits , enabling communication between sensory or motor neurons and the central nervous system (CNS). [ 2 ]
Different neurotransmitters are released from different interneurons, but the two most common neurotransmitters are GABA, the primary inhibitory neurotransmitter and glutamate, the primary excitatory neurotransmitter. [9] [10] Acetylcholine is a neurotransmitter that often activates interneurons by binding to a receptor on the membrane. [11]
A multipolar neuron is a type of neuron that possesses a single axon and many dendrites (and dendritic branches), allowing for the integration of a great deal of information from other neurons.
Upper motor neurons (UMNs) is a term introduced by William Gowers in 1886. They are found in the cerebral cortex and brainstem and carry information down to activate interneurons and lower motor neurons, which in turn directly signal muscles to contract or relax.
Example: interneurons in neurostriatum. Phasic or bursting. Neurons that fire in bursts are called phasic. Fast-spiking. Some neurons are notable for their high firing rates, for example, some types of cortical inhibitory interneurons, cells in globus pallidus, retinal ganglion cells. [24] [25]
One example of GABAergic interneurons that the GEs guide are parvalbumin-containing interneurons in the neocortex. Some examples of non-GABAergic interneurons that the GEs guide are dopaminergic interneurons in the olfactory bulb, and cholinergic interneurons in the striatum. Cells migrating along these pathways move at different rates.
The anterior grey column is made up of alpha motor neurons, gamma motor neurons, and small neurons thought to be interneurons. [2] It affects the skeletal muscles . The posterior grey column receives several types of sensory information regarding touch and sensation from receptors in the skin, bones, and joints, including fine touch ...
Chandelier cells or chandelier neurons are a subset of GABAergic cortical interneurons. They are described as parvalbumin-containing and fast-spiking to distinguish them from other subtypes of GABAergic neurons, although some studies have suggested that only a subset of chandelier cells test positive for parvalbumin by immunostaining. [3]