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2. Phases of clinical research - Wikipedia

   en.wikipedia.org/wiki/Phases_of_clinical_research

   Phase II clinical programs historically have experienced the lowest success rate of the four development phases. In 2010, the percentage of Phase II trials that proceeded to Phase III was 18%, [16] and only 31% of developmental candidates advanced from Phase II to Phase III in a study of trials over 2006–2015. [17]

3. Clinical trial - Wikipedia

   en.wikipedia.org/wiki/Clinical_trial

   Phase II-a is specifically designed to assess dosing requirements (how much drug should be given), [13] [45] while a Phase II-b trial is designed to determine efficacy (100–300 people), [1] assessing how well the drug works at the prescribed dose(s) to establish a therapeutic dose range and monitor for possible side effects. [45] Phase III

4. Dose-ranging study - Wikipedia

   en.wikipedia.org/wiki/Dose-ranging_study

   A dose-ranging study is a clinical trial where different doses of an agent (e.g. a drug) are tested against each other to establish which dose works best and/or is least harmful. Dose-ranging is usually a pre-clinical, phase I or early phase II clinical trial.

5. Evaxion completes dosing in phase 2 trial with personalized ...

   lite.aol.com/tech/story/0022/20250115/1001043220.htm

   Trial remains on track for completion and data readout in the second half of 2025; COPENHAGEN, Denmark, January 15, 2025 - Evaxion Biotech A/S (NASDAQ: EVAX) (“Evaxion”), a clinical-stage TechBio company specializing in developing AI-Immunology™ powered vaccines, has now completed the dosing of all 16 patients in its phase 2 trial with the company’s lead asset EVX-01.

6. Adaptive design (medicine) - Wikipedia

   en.wikipedia.org/wiki/Adaptive_design_(medicine)

   I-SPY 2 is an adaptive clinical trial of multiple Phase 2 treatment regimens combined with standard chemotherapy. I-SPY 2 linked 19 academic cancer centers, two community centers, the FDA, the NCI, pharmaceutical and biotech companies, patient advocates and philanthropic partners.

7. Phase II clinical trial - Wikipedia

   en.wikipedia.org/?title=Phase_II_clinical_trial&...

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