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  2. History of general anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_general_anesthesia

    On 30 March 1842, he administered diethyl ether by inhalation to a man named James Venable, in order to remove a tumor from the man's neck. [101] Long later removed a second tumor from Venable, again under ether anesthesia. He went on to employ ether as a general anesthetic for limb amputations and childbirth. Long, however, did not publish his ...

  3. Guedel's classification - Wikipedia

    en.wikipedia.org/wiki/Guedel's_classification

    Since 1982, ether is not used in the United States. [7] Now, because of the use of intravenous induction agents with muscle relaxants and the discontinuation of ether, elements of Guedel's classification have been superseded by depth of anaesthesia monitoring devices such as the BIS monitor; [5] however, the use of BIS monitoring remains ...

  4. Edward Gilbert Abbott - Wikipedia

    en.wikipedia.org/wiki/Edward_Gilbert_Abbott

    The MGH Department of Anesthesia, Critical Care and Pain Medicine traces its roots back to the October 16, 1846 public demonstration of medical ether. Edward Gilbert Abbott (1825–1855) was the patient upon whom William T. G. Morton first publicly demonstrated the use of ether as a surgical anesthetic .

  5. Inhalational anesthetic - Wikipedia

    en.wikipedia.org/wiki/Inhalational_anesthetic

    Chloroform is a much stronger and effective anaesthetic than ether, it is non-inflammable and it did not irritate the airways, unlike ether. First non-gaseous inhalational anaesthetics such as ether and chloroform were inhaled from a handkerchief which the liquid was poured on and allowed to evaporate.

  6. Theories of general anaesthetic action - Wikipedia

    en.wikipedia.org/wiki/Theories_of_general...

    The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.

  7. Ether Dome - Wikipedia

    en.wikipedia.org/wiki/Ether_Dome

    Ether Day, or The First Operation Under Ether (Robert C. Hinckley, 1882–1893) is on display at UMass Chan Medical School's Lamar Soutter library. Painter Robert Cutler Hinckley meticulously researched the event, particularly who was present and participating, for his The First Operation with Ether (1882–1893). He interviewed various Boston ...

  8. Halogenated ether - Wikipedia

    en.wikipedia.org/wiki/Halogenated_ether

    Inhaled agents like diethyl ether are critical in anesthesia. Diethyl ether initially replaced non-flammable (but more toxic) halogenated hydrocarbons like chloroform and trichloroethylene. Halothane is a halogenated hydrocarbon anesthetic agent that was introduced into clinical practice in 1956. Due to its ease of use and improved safety ...

  9. Anaesthetic machine - Wikipedia

    en.wikipedia.org/wiki/Anaesthetic_machine

    Historically, ether (the first volatile agent) was first used by John Snow's inhaler (1847) but was superseded by the use of chloroform (1848). Ether then slowly made a revival (1862–1872) with regular use via Curt Schimmelbusch's "mask", a narcosis mask for dripping liquid ether. Now obsolete, it was a mask constructed of wire, and covered ...