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The DA2PPC vaccine protects against the debilitating and deadly disease canine distemper. This disease is a fatal viral illness that causes neurologic dysfunction, pneumonia, nonspecific systemic symptoms such as fever and fatigue, and weight loss, as well as upper respiratory symptoms and diarrhea, poor appetite, and vomiting. [4]
Canine distemper virus (CDV) (sometimes termed "footpad disease") is a viral disease that affects a wide variety of mammal families, [2] including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felines, as well as pinnipeds, some primates, and a variety of other species.
What is distemper? Canine distemper is a viral disease caused by the canine distemper virus, or CDV, according to VCA Animal Hospitals. It can infect dogs, as well as other animals – including ...
Canine distemper is an often fatal infectious disease that mainly has respiratory and neurological signs. [4] Canine influenza is a newly emerging infectious respiratory disease. Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent. [5]
Vaccination of dogs is the practice of animal vaccination applied to dogs. Programs in this field have contributed both to the health of dogs and to the public health . In countries where routine rabies vaccination of dogs is practiced, for example, rabies in humans is reduced to a very rare event.
Adverse effects of vaccinations are mild, but the most common effect observed up to 30 days after administration is nasal discharge. [8] Vaccinations are not always effective. In one study it was found that 43.3% of all dogs in the study population with respiratory disease had in fact been vaccinated.
Live-attenuated vaccines use a weakened form of the virus or bacteria that causes the disease. This form of inoculation is the closest to the actual infection, and thus it has been seen to have a stronger effect than the other types of conventional vaccines. [26] Albeit, there have been some safety issues related to live-attenuated vaccines.
The canine distemper vaccination in particular has been a suspected causal factor due to the significant number of overlapping symptoms observed between systemically affected HOD puppies and dogs suffering from distemper, [9] but to-date, no definitive linkage has been demonstrated. [10] The cause of canine HOD largely remains unknown.